Found 32 matching trials
Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S PHASE1 The purpose of this study is to see if two new malaria vaccines called FMP1...
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WRAIR Clinical Trials Center
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Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 PHASE1 Objectives:
Primary:
• To characterize the infectivity of the new lot of ...
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Walter Reed Army Institute of Research
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A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine Candidates PHASE1 This study aims to assess the safety and effectiveness of four new candidat...
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Centre for Clinical Vaccinology and Tropical Medicine
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DSM265 Prophylaxis of Plasmodium Falciparum Malaria PHASE1 The study is a single centre, randomised, placebo-controlled, double-blind ...
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Fred Hutchinson Cancer Research Center - Prevention Center
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Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites PHASE1 This Phase 1 trial will include 16 subjects who will receive the Geneticall...
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Kaiser Permanente Washington Health Research Institute
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Malaria Challenge With NF54 Strain PHASE1 The purpose of this study is to determine how many infected mosquito bites ...
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University of Maryland School of Medicine - Center for Vaccine Development - Baltimore
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Trial to Evaluate L9LS in Healthy Adults PHASE1 Background:
Malaria is a parasitic disease carried by mosquitoes in tropic...
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National Institutes of Health Clinical Center
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A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1 PHASE1 This is an open label, multi-centre phase I/IIa sporozoite-challenge trial ...
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Wellcome Trust CRF, Southampton General Hospital
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Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis NA Malaria is one of the major infectious diseases in the world with a tremend...
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Radboud University Nijmegen Medical Centre
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Reproducibility of Malaria Challenge in Healthy Volunteers PHASE1 This is a prospective, single arm, single intervention safety and immunogen...
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Seattle Biomedical Research Institue's Malaria Clinical Trial Center
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